From our experience, Jello liquor mixtures will work up to the point where about 1/2 of the total water volume is replaced with liquor. So, if the Jello packet says to add dissolve in 1 cup, then add 1 more cup after, you can safely replace approx 1 cup of water with your moonshine.
Be aware of the proof of your shine! Adding 1 cup of plain store bought Vodka vs. adding 1 cup of your fire-breathing shine is a big difference!
Feeling adventurous? Try hollowing out some lime halves to pour/set the mixture in instead of the cups!